To read the original work by Logan Click here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1815464/
Simplicity is the ultimate sophistication : Lenoardo da Vinci
The simply titled work by VS Logan brought to existence a much used (and misused) criterion for the diagnosis of abdominal tuberculosis : The response to therapy. Published in 1969, this was an important addition to the traditional Paustian criteria. The Paustian criteria which were based on histological, operative, animal inoculation and microbiological findings often were found wanting to diagnose intestinal tuberculosis (ITB) and in discriminating from Crohn’s disease (CD). In a 10 year period, Logan identified three groups of diagnosis: Group 1 with microbiological positivity in 4 patients, Group 2 with caseating granulomas in 6 patients and Group 3 where presence of ‘sarcoid like granuloma’ in 2 cases without any other evidence of Crohn’s disease and a response to therapy. The paper describes response to therapy as “both healed without recurrence after surgery plus chemotherapy”. This response to therapy remains an important armamentarium to discriminate the two conditions.